Publications

  • Type

2019

Jensen, S., B. T. Sullivan, D. A. Hartzler, J. Meza Aguilar, S. Awel, S. Bajt, S. Basu, R. Bean, H. Chapman, C. Conrad, M. Frank, R. Fromme, J. M. Martin-Garcia, T. D. Grant, M. Heymann, M. S. Hunter, G. Ketawala, R. A. Kirian, J. Knoska, C. Kupitz, X. Li, M. Liang, S. Lisova, V. Mariani, V. L. Mazalova, M. Messerschmidt, M. Moran, G. Nelson, D. Oberthuer, A. Schaffer, R. G. Sierra, N. Vaughn, U. Weierstall, M. O. Wiedorn, P. L. Xavier, J. H. Yang, O. Yefanov, N. Zatsepin, A. L. Aquila, P. Fromme, S. Boutet, G. T. Seidler and Y. N. Pushkar (2019). “X-ray Emission Spectroscopy at X-ray Free Electron Lasers: Limits to Observation of the Classical Spectroscopic Response for Electronic Structure Analysis.” J Phys Chem Lett. 10(3):441-446.

DOI: 10.1021/acs.jpclett.8b03595.

Journal article.


2018

Gisriel, C., S. Saroussi, S. Ramundo, P. Fromme and Govindjee (2018). “Gordon Research Conference on photosynthesis: photosynthetic plasticity from the environment to synthetic systems.” Photosynth Res 136(3): 393-405.

DOI: 10.1007/s11120-017-0472-x.

Journal article.

Hansen, D. T., F. M. Craciunescu, P. Fromme, S. A. Johnston and K. F. Sykes (2018). “Generation of High-Specificity Antibodies against Membrane Proteins Using DNA-Gold Micronanoplexes for Gene Gun Immunization.” Curr Protoc Protein Sci 91: 29 20 21-29 20 22.

DOI: 10.1002/cpps.50.

Journal article.

Lan, T. Y., J. L. Wierman, M. W. Tate, H. T. Philipp, J. M. Martin-Garcia, L. Zhu, D. Kissick, P. Fromme, R. F. Fischetti, W. Liu, V. Elser and S. M. Gruner (2018). “Solving protein structure from sparse serial microcrystal diffraction data at a storage-ring synchrotron source.” IUCrJ 5(Pt 5): 548-558.

DOI: 10.1107/S205225251800903X.

Journal article.

Lee, D. B., J. M. Kim, J. H. Seok, J. H. Lee, J. D. Jo, J. Y. Mun, C. Conrad, J. Coe, G. Nelson, B. Hogue, T. A. White, N. Zatsepin, U. Weierstall, A. Barty, H. Chapman, P. Fromme, J. Spence, M. S. Chung, C. H. Oh and K. H. Kim (2018). “Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography.” Sci Rep 8(1): 2541.

DOI: 10.1038/s41598-018-20899-9.

Journal article.

Olmos, J. L., Jr., S. Pandey, J. M. Martin-Garcia, G. Calvey, A. Katz, J. Knoska, C. Kupitz, M. S. Hunter, M. Liang, D. Oberthuer, O. Yefanov, M. Wiedorn, M. Heyman, M. Holl, K. Pande, A. Barty, M. D. Miller, S. Stern, S. Roy-Chowdhury, J. Coe, N. Nagaratnam, J. Zook, J. Verburgt, T. Norwood, I. Poudyal, D. Xu, J. Koglin, M. H. Seaberg, Y. Zhao, S. Bajt, T. Grant, V. Mariani, G. Nelson, G. Subramanian, E. Bae, R. Fromme, R. Fung, P. Schwander, M. Frank, T. A. White, U. Weierstall, N. Zatsepin, J. Spence, P. Fromme, H. N. Chapman, L. Pollack, L. Tremblay, A. Ourmazd, G. N. Phillips, Jr. and M. Schmidt (2018). “Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography.” BMC Biol 16(1): 59.

DOI: 10.1186/s12915-018-0524-5.

Journal article.

Pande, K., J. J. Donatelli, E. Malmerberg, L. Foucar, B. K. Poon, M. Sutter, S. Botha, S. Basu, R. Bruce Doak, K. Dorner, S. W. Epp, L. Englert, R. Fromme, E. Hartmann, R. Hartmann, G. Hauser, J. Hattne, A. Hosseinizadeh, S. Kassemeyer, L. Lomb, S. F. C. Montero, A. Menzel, D. Rolles, A. Rudenko, M. M. Seibert, R. G. Sierra, P. Schwander, A. Ourmazd, P. Fromme, N. K. Sauter, M. Bogan, J. Bozek, C. Bostedt, I. Schlichting, C. A. Kerfeld and P. H. Zwart (2018). “Free-electron laser data for multiple-particle fluctuation scattering analysis.” Sci Data 5: 180201.

DOI: 10.1038/sdata.2018.201.

Journal article.

Wiedorn, M. O., D. Oberthur, R. Bean, R. Schubert, N. Werner, B. Abbey, M. Aepfelbacher, L. Adriano, A. Allahgholi, N. Al-Qudami, J. Andreasson, S. Aplin, S. Awel, K. Ayyer, S. Bajt, I. Barak, S. Bari, J. Bielecki, S. Botha, D. Boukhelef, W. Brehm, S. Brockhauser, I. Cheviakov, M. A. Coleman, F. Cruz-Mazo, C. Danilevski, C. Darmanin, R. B. Doak, M. Domaracky, K. Dorner, Y. Du, H. Fangohr, H. Fleckenstein, M. Frank, P. Fromme, A. M. Ganan-Calvo, Y. Gevorkov, K. Giewekemeyer, H. M. Ginn, H. Graafsma, R. Graceffa, D. Greiffenberg, L. Gumprecht, P. Gottlicher, J. Hajdu, S. Hauf, M. Heymann, S. Holmes, D. A. Horke, M. S. Hunter, S. Imlau, A. Kaukher, Y. Kim, A. Klyuev, J. Knoska, B. Kobe, M. Kuhn, C. Kupitz, J. Kupper, J. M. Lahey-Rudolph, T. Laurus, K. Le Cong, R. Letrun, P. L. Xavier, L. Maia, F. Maia, V. Mariani, M. Messerschmidt, M. Metz, D. Mezza, T. Michelat, G. Mills, D. C. F. Monteiro, A. Morgan, K. Muhlig, A. Munke, A. Munnich, J. Nette, K. A. Nugent, T. Nuguid, A. M. Orville, S. Pandey, G. Pena, P. Villanueva-Perez, J. Poehlsen, G. Previtali, L. Redecke, W. M. Riekehr, H. Rohde, A. Round, T. Safenreiter, I. Sarrou, T. Sato, M. Schmidt, B. Schmitt, R. Schonherr, J. Schulz, J. A. Sellberg, M. M. Seibert, C. Seuring, M. L. Shelby, R. L. Shoeman, M. Sikorski, A. Silenzi, C. A. Stan, X. Shi, S. Stern, J. Sztuk-Dambietz, J. Szuba, A. Tolstikova, M. Trebbin, U. Trunk, P. Vagovic, T. Ve, B. Weinhausen, T. A. White, K. Wrona, C. Xu, O. Yefanov, N. Zatsepin, J. Zhang, M. Perbandt, A. P. Mancuso, C. Betzel, H. Chapman and A. Barty (2018). “Megahertz serial crystallography.” Nat Commun 9(1): 4025.

DOI: 10.1038/s41467-018-06156-7.

Journal article.

Wiedorn, M. O., S. Awel, A. J. Morgan, K. Ayyer, Y. Gevorkov, H. Fleckenstein, N. Roth, L. Adriano, R. Bean, K. R. Beyerlein, J. Chen, J. Coe, F. Cruz-Mazo, T. Ekeberg, R. Graceffa, M. Heymann, D. A. Horke, J. Knoska, V. Mariani, R. Nazari, D. Oberthur, A. K. Samanta, R. G. Sierra, C. A. Stan, O. Yefanov, D. Rompotis, J. Correa, B. Erk, R. Treusch, J. Schulz, B. G. Hogue, A. M. Ganan-Calvo, P. Fromme, J. Kupper, A. V. Rode, S. Bajt, R. A. Kirian and H. N. Chapman (2018). “Rapid sample delivery for megahertz serial crystallography at X-ray FELs.” IUCrJ 5(Pt 5): 574-584.

DOI: 10.1107/S2052252518008369.

Journal article.

Woitowich, N. C., A. S. Halavaty, P. Waltz, C. Kupitz, J. Valera, G. Tracy, K. D. Gallagher, E. Claesson, T. Nakane, S. Pandey, G. Nelson, R. Tanaka, E. Nango, E. Mizohata, S. Owada, K. Tono, Y. Joti, A. C. Nugent, H. Patel, A. Mapara, J. Hopkins, P. Duong, D. Bizhga, S. E. Kovaleva, R. St Peter, C. N. Hernandez, W. B. Ozarowski, S. Roy-Chowdhuri, J. H. Yang, P. Edlund, H. Takala, J. Ihalainen, J. Brayshaw, T. Norwood, I. Poudyal, P. Fromme, J. C. H. Spence, K. Moffat, S. Westenhoff, M. Schmidt and E. A. Stojkovic (2018). “Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome.” IUCrJ 5(Pt 5): 619-634.

DOI: 10.1107/S2052252518010631.

Journal article.


2017

Deb A, Johnson WA, Kline AP, Scott BJ, Meador LR, Srinivas D, Martin-Garcia JM, Dorner K, Borges CR, Misra R, Hogue BG, Fromme P, and Mor TS. (2017) Bacterial expression, correct membrane targeting and functional folding of the HIV-1 membrane protein Vpu using a periplasmic signal peptide. Plos One 12: e0172529.

DOI: 10.1371/journal.pone.0172529.

Journal article.

Fromme P, and Spence JCH. (2017) Split-Second Reactions. Scientific American 316: 62-67.

DOI: 10.1038/scientificamerican0517-62.

Journal article.

Gati C, Oberthuer D, Yefanov O, Bunker RD, Stellato F, Chiu E, Yeh SM, Aquila A, Basu S, Bean R, Beyerlein KR, Botha S, Boutet S, DePonte DP, Doak RB, Fromme R, Galli L, Grotjohann I, James DR, Kupitz C, Lomb L, Messerschmidt M, Nass K, Rendek K, Shoeman RL, Wang D, Weierstall U, White TA, Williams GJ, Zatsepin NA, Fromme P, Spence JC, Goldie KN, Jehle JA, Metcalf P, Barty A, and Chapman HN. (2017) Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser. Proc Natl Acad Sci U S A 114: 2247-2252

DOI: 10.1073/pnas.1609243114.

Journal article.

Ishigami I, Zatsepin NA, Hikita M, Conrad CE, Nelson G, Coe JD, Basu S, Grant TD, Seaberg MH, Sierra RG, Hunter MS, Fromme P, Fromme R, Yeh SR, and Rousseau DL. (2017) Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature. Proc Natl Acad Sci U S A 114: 8011-8016.

DOI: 10.1073/pnas.1705628114.

Journal article.

Kupitz, C., Olmos, J.L., Jr., Holl, M., Tremblay, L., Pande, K., Pandey, S., Oberthur, D., Hunter, M., Liang, M., Aquila, A., Tenboer, J., Calvey, G., Katz, A., Chen, Y., Wiedorn, M.O., Knoska, J., Meents, A., Majriani, V., Norwood, T., Poudyal, I., Grant, T., Miller, M.D., Xu, W., Tolstikova, A., Morgan, A., Metz, M., Martin-Garcia, J.M., Zook, J.D., Roy-Chowdhury, S., Coe, J., Nagaratnam, N., Meza, D., Fromme, R., Basu, S., Frank, M., White, T., Barty, A., Bajt, S., Yefanov, O., Chapman, H.N., Zatsepin, N., Nelson, G., Weierstall, U., Spence, J., Schwander, P., Pollack, L., Fromme, P., Ourmazd, A., Phillips, G.N., Jr., Schmidt, M. (2017) Structural enzymology using X-ray free electron lasers. Struct Dyn, 4(4), 044003.

DOI: 10.1063/1.4972069.

Journal article.

Kurta, Ruslan P., Donatelli, Jeffrey J., Yoon, Chun Hong, Berntsen, Peter, Bielecki, Johan, Daurer, Benedikt J., DeMirci, Hasan, Fromme, Petra, Hantke, Max Felix, Maia, Filipe R. N. C., Munke, Anna, Nettelblad, Carl, Pande, Kanupriya, Reddy, Hemanth, K. N., Sellberg, Jonas A., Sierra, Raymond G., Svenda, Martin, van der Schot, Gijs, Vartanyants, Ivan A., Williams, Garth J., Xavier, P. Lourdu, Aquila, Andrew, Zwart, Peter H., and Mancuso, Adrian P. (2017) Correlations in scattered x-ray laser pulses reveal nanoscale structural features of viruses. Physical Review Letters, 119(15): 158102

DOI: 10.1103/PhysRevLett.119.158102.

Journal article.

Li X, Chiu CY, Wang HJ, Kassemeyer S, Botha S, Shoeman RL, Lawrence RM, Kupitz C, Kirian R, James D, Wang D, Nelson G, Messerschmidt M, Boutet S, Williams GJ, Hartmann E, Jafarpour A, Foucar LM, Barty A, Chapman H, Liang M, Menzel A, Wang F, Basu S, Fromme R, Doak RB, Fromme P, Weierstall U, Huang MH, Spence JC, Schlichting I, Hogue BG, and Liu H. (2017) Diffraction data of core-shell nanoparticles from an X-ray free electron laser. Sci Data 4: 170048.

DOI: 10.1038/sdata.2017.48.

Journal article.

Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J, Zhu L, Geiger J, Chun E, Kissick D, Hilgart MC, Ogata C, Ishchenko A, Nagaratnam N, Roy-Chowdhury S, Coe J, Subramanian G, Schaffer A, James D, Ketwala G, Venugopalan N, Xu S, Corcoran S, Ferguson D, Weierstall U, Spence JCH, Cherezov V, Fromme P, Fischetti RF, and Liu W. (2017) Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCRJ 4: 439-454.

DOI: 10.1107/S205225251700570X.

Journal article.

Reddy HKN, Yoon CH, Aquila A, Awel S, Ayyer K, Barty A, Berntsen P, Bielecki J, Bobkov S, Bucher M, Carini GA, Carron S, Chapman H, Daurer B, DeMirci H, Ekeberg T, Fromme P, Hajdu J, Hanke MF, Hart P, Hogue BG, Hosseinizadeh A, Kim Y, Kirian RA, Kurta RP, Larsson DSD, Duane Loh N, Maia F, Mancuso AP, Muhlig K, Munke A, Nam D, Nettelblad C, Ourmazd A, Rose M, Schwander P, Seibert M, Sellberg JA, Song C, Spence JCH, Svenda M, Van der Schot G, Vartanyants IA, Williams GJ, and Xavier PL. (2017) Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source. Sci Data 4: 170079.

DOI: 10.1038/sdata.2017.79.

Journal article.

Stagno, J.R., Liu, Y., Bhandari, Y.R., Conrad, C.E., Panja, S., Swain, M., Fan, L., Nelson, G., Li, C., Wendel, D.R., White, T.A., Coe, J.D., Wiedorn, M.O., Knoska, J., Oberthuer, D., Tuckey, R.A., Yu, P., Dyba, M., Tarasov, S.G., Weierstall, U., Grant, T.D., Schwieters, C.D., Zhang, J., Ferre-D’Amare, A.R., Fromme, P., Draper, D.E., Liang, M., Hunter, M.S., Boutet, S., Tan, K., Zuo, X., Ji, X., Barty, A., Zatsepin, N.A., Chapman, H.N., Spence, J.C., Woodson, S.A., Wang, Y.X. (2017) Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541(7636), 242-246.

DOI: 10.1038/nature20599.

Journal article.


2016

Abdallah, B.G., Roy-Chowdhury, S., Fromme, R., Fromme, P., Ros, A. (2016) Protein Crystallization in an Actuated Microfluidic Nanowell Device. Crystal Growth & Design, 16(4), 2074-2082.

DOI: 10.1021/acs.cgd.5b01748.

Journal article.

Ayyer, K., Yefanov, O.M., Oberthur, D., Roy-Chowdhury, S., Galli, L., Mariani, V., Basu, S., Coe, J., Conrad, C.E., Fromme, R., Schaffer, A., Droner, K., James, D., Kupitz, C., Metz, M., Nelson, G., Xavier, P.L., Beyerlein, K.R., Schmidt, M., Sarrou, I., Spence, J.C.H., Weierstall, U., White, T.A., Yang, J.H., Zhao, Y., Liang, M.N., Aquila, A., Hunter, M.S., Robinson, J.S., Koglin, J.E., Boutet, S., Fromme, P., Barty, A., Chapman, H.N. (2016) Macromolecular diffractive imaging using imperfect crystals. Nature, 530(7589), 202-206.

DOI: 10.1038/nature16949.

Journal article.

Coe, J. and Fromme, P. (2016) Serial Femtosecond Crystallography Opens New Avenues for Structural Biology. Protein and Peptide Letters, 23(3), 255-272.

DOI: 10.2174/0929866523666160120152937.

Journal article.

Dorner, K., Martin-Garcia, J.M., Kupitz, C., Gong, Z., Mallet, T.C., Chen, L.Q., Wachter, R.M., Fromme, P. (2016) Characterization of Protein Nanocrystals Based on the Reversibility of Crystallization. Crystal Growth & Design, 16(7), 3838-3845.

DOI: 10.1021/acs.cgd.6b00384.

Journal article.

Dow, X.Y., Dettmar, C.M., DeWalt, E.L., Newman, J.A., Dow, A.R., Roy-Chowdhury, S., Coe, J.D., Kupitz, C., Fromme, P., Simpson, G.J. (2016) Second harmonic generation correlation spectroscopy for characterizing translationally diffusing protein nanocrystals. Acta Crystallographica Section D-Structural Biology, 72, 849-859.

DOI: 10.1107/S205979831600841X.

Journal article.

Edlund, P., Takala, H., Claesson, E., Henry, L., Dods, R., Lehtivuori, H., Panman, M., Pande, K., White, T., Nakane, T., Berntsson, O., Gustavsson, E., Bath, P., Modi, V., Roy-Chowdhury, S., Zook, J., Berntsen, P., Pandey, S., Poudyal, I., Tenboer, J., Kupitz, C., Barty, A., Fromme, P., Koralek, J.D., Tanaka, T., Spence, J., Liang, M.L., Hunter, M.S., Boutet, S., Nango, E., Moffat, K., Groenhof, G., Ihalainen, J., Stojkovic, E.A., Schmidt, M., Westenhoff, S. (2016) The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography. Scientific Reports, 6: 35279.

DOI: 10.1038/srep35279.

Journal article.

Fromme, P. and Sali, A. (2016) Editorial overview: Biophysical and molecular biological methods. Current Opinion in Structural Biology, 40, Ix-Xi.

DOI: 10.1016/j.sbi.2016.11.015.

Journal article.

Hansen, D.T., Robida, M.D., Craciunescu, F.M., Loskutov, A.V., Dorner, K., Rodenberry, J.C., Wang, X., Olson, T.L., Patel, H., Fromme, P., Sykes, K.F. (2016) Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization. Scientific Reports, 6: 21925.

DOI: 10.1038/srep21925.

Journal article.

Herascu, N., Hunter, M.S., Shafiei, G., Najafi, M., Johnson, T.W., Fromme, P., Zazubovich, V. (2016) Spectral Hole Burning in Cyanobacterial Photosystem I with P700 in Oxidized and Neutral States. Journal of Physical Chemistry B, 120(40), 10483-10495.

DOI: 10.1021/acs.jpcb.6b07803.

Journal article.

Kärtner, F.X., Ahr, F., Calendron, A.L., Cankaya, H., Carbajo, S., Chang, G., Cirmi, G., Dorner, K., Dorda, U., Fallahi, A., Hartin, A., Hemmer, M., Hobbs, R., Hua, Y., Huang, W.R., Letrun, R., Maths, N., Mazalova, V., Mucke, O.D., Nanni, E., Putnam, W., Ravi, K., Reichert, F., Sarrou, I., Wu, X., Yahaghi, A., Ye, H., Zapata, L., Zhang, D., Zhou, C., Miller, R.J.D., Berggren, K.K., Graafsma, H., Meents, A., Assmann, R.W., Chapman, H.N., Fromme, P. (2016) AXSIS: Exploring the frontiers in attosecond X-ray science, imaging and spectroscopy. Nuclear Instruments & Methods in Physics Research Section a-Accelerators Spectrometers Detectors and Associated Equipment, 829, 24-29.

DOI: 10.1016/j.nima.2016.02.080.

Journal article.

Kessans, S.A., Linhart, M.D., Meador, L.R., Kilbourne, J., Hogue, B.G., Fromme, P., Matoba, N., Mor, T.S. (2016) Immunological Characterization of Plant-Based HIV-1 Gag/Dgp41 Virus-Like Particles. Plos One, 11(3): e0151842.

DOI: 10.1371/journal.pone.0151842.

Journal article.

Martin-Garcia, J.M., Conrad, C.E., Coe, J., Roy-Chowdhury, S., Fromme, P. (2016) Serial femtosecond crystallography: A revolution in structural biology. Archives of Biochemistry and Biophysics, 602, 32-47.

DOI: 10.1016/j.abb.2016.03.036.

Journal article.

Munke, A., Andreasson, J., Aquila, A., Awel, S., Ayyer, K., Barty, A., Bean, R.J., Berntsen, P., Bielecki, J., Boutet, S., Bucher, M., Chapman, H.N., Daurer, B.J., DeMirci, H., Elser, V., Fromme, P., Hajdu, J., Hantke, M.F., Higashiura, A., Hogue, B.G., Hosseinizadeh, A., Kim, Y., Kirian, R.A., Reddy, H.K.N., Lan, T.Y., Larsson, D.S.D., Liu, H.G., Loh, N.D., Maia, F.R.N.C., Mancuso, A.P., Muhlig, K., Nakagawa, A., Nam, D., Nelson, G., Nettelblad, C., Okamoto, K., Ourmazd, A., Rose, M., van der Schot, G., Schwander, P., Seibert, M.M., Sellberg, J.A., Sierra, R.G., Song, C.Y., Svenda, M., Timneanu, N., Vartanyants, I.A., Westphal, D., Wiedorn, M.O., Williams, G.J., Xavier, P.L., Yoon, C.H., Zook, J. (2016) Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source. Scientific Data, 3, 160064.

DOI: 10.1038/sdata.2016.64.

Journal article.

Nogly, P., Panneels, V., Nelson, G., Gati, C., Kimura, T., Milne, C., Milathianaki, D., Kubo, M., Wu, W.T., Conrad, C., Coe, J., Bean, R., Zhao, Y., Bath, P., Dods, R., Harimoorthy, R., Beyerlein, K.R., Rheinberger, J., James, D., DePonte, D., Li, C.F., Sala, L., Williams, G.J., Hunter, M.S., Koglin, J.E., Berntsen, P., Nango, E., Iwata, S., Chapman, H.N., Fromme, P., Frank, M., Abela, R., Boutet, S., Barty, A., White, T.A., Weierstall, U., Spence, J., Neutze, R., Schertler, G., Standfuss, J. (2016) Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography. Nature Communications, 7, 12314.

DOI: 10.1038/ncomms12314.

Journal article.

Pande, K., Hutchison, C.D.M., Groenhof, G., Aquila, A., Robinson, J.S., Tenboer, J., Basu, S., Boutet, S., DePonte, D.P., Liang, M.N., White, T.A., Zatsepin, N.A., Yefanov, O., Morozov, D., Oberthuer, D., Gati, C., Subramanian, G., James, D., Zhao, Y., Koralek, J., Brayshaw, J., Kupitz, C., Conrad, C., Roy-Chowdhury, S., Coe, J.D., Metz, M., Xavier, P.L., Grant, T.D., Koglin, J.E., Ketawala, G., Fromme, R., Srajer, V., Henning, R., Spence, J.C.H., Ourmazd, A., Schwander, P., Weierstall, U., Frank, M., Fromme, P., Barty, A., Chapman, H.N., Moffat, K., van Thor, J.J., Schmidt, M. (2016) Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein. Science, 352(6286), 725-729.

DOI: 10.1126/science.aad5081.

Journal article.

Zhou, X.E., Gao, X., Barty, A., Kang, Y.Y., He, Y.Z., Liu, W., Ishchenko, A., White, T.A., Yefanov, O., Han, G.W., Xu, Q.P., de Waal, P.W., Suino-Powell, K.M., Boutet, S., Williams, G.J., Wang, M.T., Li, D.F., Caffrey, M., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Stevens, R.C., Cherezov, V., Melcher, K., Xu, H.E. (2016) X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Scientific Data, 3, 160021.

DOI: 10.1038/sdata.2016.21.

Journal article.


2015

Abdallah BG, Zatsepin NA, Roy-Chowdhury S, Coe J, Conrad CE, Dorner K, Sierra RG, Stevenson HP, Camacho-Alanis F, Grant TD, Nelson G, James D, Calero G, Wachter RM, Spence JCH, Weierstall U, Fromme P, Ros A (2015) Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction. Structural Dynamics 2(4): e041719.

DOI: 10.1063/1.4928688.

Journal article.

Abdallah, B.G., S. Roy-Chowdhury, J. Coe, P. Fromme, and A. Ros, (2015) High Throughput Protein Nanocrystal Fractionation in a Microfluidic Sorter. Analytical Chemistry, 87(8): 4159-4167.

DOI: 10.1021/acs.analchem.5b00589.

Journal article.

Chen, J., A. Kell, K. Acharya, C. Kupitz, P. Fromme, and R. Jankowiak, (2015) Critical assessment of the emission spectra of various photosystem II core complexes. Photosynthesis Research. 124(3): 253-265.

DOI: 10.1007/s11120-015-0128-7.

Journal article.

Conrad CE, Basu S, James D, Wang DJ, Schaffer A, Roy-Chowdhury S, Zatsepin NA, Aquila A, Coe J, Gati C, Hunter MS, Koglin JE, Kupitz C, Nelson G, Subramanian G, White TA, Zhao Y, Zook J, Boutet S, Cherezov V, Spence JCH, Fromme R, Weierstall U, Fromme P (2015) A novel inert crystal delivery medium for serial femtosecond crystallography. IUCrJ 2: 421-430.

DOI: 10.1107/S2052252515009811.

Journal article.

Fenalti, G., N.A. Zatsepin, C. Betti, P. Giguere, G.W. Han, A. Ishchenko, W. Liu, K. Guillemyn, H. Zhang, D. James, D. Wang, U. Weierstall, J.C.H. Spence, S. Boutet, M. Messerschmidt, G.J. Williams, C. Gati, O.M. Yefanov, T.A. White, D. Oberthuer, M. Metz, C.H. Yoon, A. Barty, H.N. Chapman, S. Basu, J. Coe, C.E. Conrad, R. Fromme, P. Fromme, D. Tourwé, P.W. Schiller, B.L. Roth, S. Ballet, V. Katritch, R.C. Stevens, and V. Cherezov, (2015) Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nat Struct Mol Biol,  22(3): 265-268.

DOI: 10.1038/nsmb.2965.

Journal article.

Fromme R, Ishchenko A, Metz M, Chowdhury SR, Basu S, Boutet S, Fromme P, White TA, Barty A, Spence JCH, Weierstall U, Liu W, Cherezov V (2015) Serial femtosecond crystallography of soluble proteins in lipidic cubic phase. IUCrJ 2(5): 545-551.

DOI: 10.1107/S2052252515013160.

Journal article.

Fromme, P (2015) XFELs open a new era in structural chemical biology, Nature Chemical Biology 11, 895-899.

DOI: 10.1038/nchembio.1968.

Journal article.

Gong Z, Martin-Garcia JM, Daskalova SM, Craciunescu FM, Song LS, Dorner K, Hansen DT, Yang JH, LaBaer J, Hogue BG, Mor TS, Fromme P (2015) Biophysical Characterization of a Vaccine Candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion. PloS One, 10 (8) e0136507

DOI: 10.1371/journal.pone.0136507.

Journal article.

Kang YY, Zhou XE, Gao X, He YZ, Liu W, Ishchenko A, Barty A, Sathish D, Yefanov O, Han GW, Xu QP, de Waal PW, Ke JY, Tan MHE, Zhang CH, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma JM, Zhi XY, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang DJ, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu HG, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan MJ, Yang HY, Li J, Wang MT, Zheng Z, Li DF, Howe N, Zhao YM, Standfuss J, Diederichs K, Dong YH, Potter CS, Carragher B, Caffrey M, Jiang HL, Chapman HN, Spence JCH, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE (2015) Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 2015, 523: 561-567.

DOI: 10.1038/nature14656.

Journal article.

Lawrence RM, Conrad CE, Zatsepin NA, Grant TD, Liu HG, James D, Nelson G, Subramanian G, Aquila A, Hunter MS, Liang MN, Boutet S, Coe J, Spence JCH, Weierstall U, Liu W, Fromme P, Cherezov V, Hogue B. (2015) Serial femtosecond X-ray diffraction of enveloped virus microcrystals. Structural Dynamics  2 (4): e041720

DOI: 10.1063/1.4929410.

Journal article.

Li D, Stansfeld PJ, Sansom MSP, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, Zatsepin NA, Cherezov V, Liu W, Bandaru S, English NJ, Gati C, Barty A, Yefanov O, Chapman HN, Diederichs K, Messerschmidt M, Boutet S, Williams GJ, Seibert MM, Caffrey M (2015) Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nature Communications 6, e10140.

DOI: 10.1038/ncomms10140.

Journal article.

Yang, J.-H., I. Sarrou, J.M. Martin-Garcia, S. Zhang, K.E. Redding, and P. Fromme, (2015) Purification and biochemical characterization of the ATP synthase from Heliobacterium modesticaldum. Protein Expression and Purification, 114: 1-8.

DOI: 10.1016/j.pep.2015.05.006.

Journal article.

Zhang, H., H. Unal, C. Gati, Gye W. Han, W. Liu, Nadia A. Zatsepin, D. James, D. Wang, G. Nelson, U. Weierstall, Michael R. Sawaya, Q. Xu, M. Messerschmidt, Garth J. Williams, S. Boutet, Oleksandr M. Yefanov, Thomas A. White, C. Wang, A. Ishchenko, Kalyan C. Tirupula, R. Desnoyer, J. Coe, Chelsie E. Conrad, P. Fromme, Raymond C. Stevens, V. Katritch, Sadashiva S. Karnik, and V. Cherezov, (2015) Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography. Cell, 161(4): 833-844.

DOI: 10.1016/j.cell.2015.04.011.

Journal article.

Zook, J., G. Mo, Nicholas J. Sisco, Felicia M. Craciunescu, Debra T. Hansen, B. Baravati, Brian R. Cherry, Kathryn Sykes, Rebekka Wachter, Wade D. Van Horn, and P. Fromme, NMR Structure of Francisella tularensis Virulence Determinant Reveals Structural Homology to Bet v1 Allergen Proteins. Structure, 2015. 23(6): 1116-1122

DOI: 10.1016/j.str.2015.03.025.

Journal article.


2014

Arnlund, D., L.C. Johansson, C. Wickstrand, A. Barty, G.J. Williams, E. Malmerberg, J. Davidsson, D. Milathianaki, D.P. DePonte, R.L. Shoeman, D. Wang, D. James, G. Katona, S. Westenhoff, T.A. White, A. Aquila, S. Bari, P. Berntsen, M. Bogan, T.B. van Driel, R.B. Doak, K.S. Kjaer, M. Frank, R. Fromme, I. Grotjohann, R. Henning, M.S. Hunter, R.A. Kirian, I. Kosheleva, C. Kupitz, M. Liang, A.V. Martin, M.M. Nielsen, M. Messerschmidt, M.M. Seibert, J. Sjohamn, F. Stellato, U. Weierstall, N.A. Zatsepin, J.C.H. Spence, P. Fromme, I. Schlichting, S. Boutet, G. Groenhof, H.N. Chapman, and R. Neutze, (2014) Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. Nat Meth, 11(9): p. 923-926.

DOI: 10.1038/nmeth.3067.

Journal article.

Flory, J.D., C.R. Simmons, S. Lin, T. Johnson, A. Andreoni, J. Zook, G. Ghirlanda, Y. Liu, H. Yan, and P. Fromme, (2014) Low Temperature Assembly of Functional 3D DNA-PNA-Protein Complexes. Journal of the American Chemical Society, 136(23): 8283-8295.

DOI: 10.1021/ja501228c.

Journal article.

Flory, J.D., T. Johnson, C.R. Simmons, S. Lin, G. Ghirlanda, and P. Fromme, (2014) Purification and assembly of thermostable Cy5 labeled γ-PNAs into a 3D DNA nanocage. Artificial DNA: PNA & XNA, 5(3): 1-8.

DOI: 10.4161/1949095X.2014.992181.

Journal article.

Fromme, P., (2014) Sources of inspiration. Nature, 505(7485): 620-621.

DOI: 10.1038/505620a.

Journal article.

Gong, Z., S.A. Kessans, L. Song, K. Dörner, H.-H. Lee, L.R. Meador, J. LaBaer, B.G. Hogue, T.S. Mor, and P. Fromme, (2014) Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41. Protein Science,  23(11): 1607-1618.

DOI: 10.1002/pro.2540.

Journal article.

Kupitz, C., I. Grotjohann, C.E. Conrad, S. Roy-Chowdhury, R. Fromme, and P. Fromme, (2014) Microcrystallization techniques for serial femtosecond crystallography using photosystem II from Thermosynechococcus elongatus as a model system. Philosophical Transactions of the Royal Society B: Biological Sciences,  369(1647): 20130316.

DOI: 10.1098/rstb.2013.0316.

Journal article.

Kupitz, C., S. Basu, I. Grotjohann, R. Fromme, N.A. Zatsepin, K.N. Rendek, M.S. Hunter, R.L. Shoeman, T.A. White, D. Wang, D. James, J.-H. Yang, D.E. Cobb, B. Reeder, R.G. Sierra, H. Liu, A. Barty, A.L. Aquila, D. Deponte, R.A. Kirian, S. Bari, J.J. Bergkamp, K.R. Beyerlein, M.J. Bogan, C. Caleman, T.-C. Chao, C.E. Conrad, K.M. Davis, H. Fleckenstein, L. Galli, S.P. Hau-Riege, S. Kassemeyer, H. Laksmono, M. Liang, L. Lomb, S. Marchesini, A.V. Martin, M. Messerschmidt, D. Milathianaki, K. Nass, A. Ros, S. Roy-Chowdhury, K. Schmidt, M. Seibert, J. Steinbrener, F. Stellato, L. Yan, C. Yoon, T.A. Moore, A.L. Moore, Y. Pushkar, G.J. Williams, S. Boutet, R.B. Doak, U. Weierstall, M. Frank, H.N. Chapman, J.C.H. Spence, and P. Fromme, (2014) Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature, 513(7517): 261-265.

DOI: 10.1038/nature13453.

Journal article.

Lee, H.-H., I. Cherni, H.Q. Yu, R. Fromme, J.D. Doran, I. Grotjohann, M. Mittman, S. Basu, A. Deb, K. Dorner, A. Aquila, A. Barty, S. Boutet, H.N. Chapman, R.B. Doak, M.S. Hunter, D. James, R.A. Kirian, C. Kupitz, R.M. Lawrence, H. Liu, K. Nass, I. Schlichting, K.E. Schmidt, M.M. Seibert, R.L. Shoeman, J.C.H. Spence, F. Stellato, U. Weierstall, G.J. Williams, C. Yoon, D. Wang, N.A. Zatsepin, B.G. Hogue, N. Matoba, P. Fromme, and T.S. Mor, (2014) Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1. IUCrJ, 1(5): 305-317.

DOI: 10.1107/S2052252514014900.

Journal article.

Martin-Garcia, J.M., D.T. Hansen, J. Zook, A.V. Loskutov, M.D. Robida, F.M. Craciunescu, K.F. Sykes, R.M. Wachter, P. Fromme, and J.P. Allen, (2014) Purification and Biophysical Characterization of the CapA Membrane Protein FTT0807 from Francisella tularensis. Biochemistry,  53(12): 1958-1970.

DOI: 10.1021/bi401644s.

Journal article.

Meza-Aguilar, J.D., P. Fromme, A. Torres-Larios, G. Mendoza-Hernández, U. Hernandez-Chiñas, R.A. Arreguin-Espinosa de los Monteros, C.A. Eslava Campos, and R. Fromme, (2014) X-ray crystal structure of the passenger domain of plasmid encoded toxin (Pet), an autotransporter enterotoxin from enteroaggregative Escherichia coli (EAEC). Biochemical and Biophysical Research Communications, 445(2): 439-444.

DOI: 10.1016/j.bbrc.2014.02.016.

Journal article.

Paul, R., R.E. Jinkerson, K. Buss, J. Steel, R. Mohr, W.R. Hess, M. Chen, and P. Fromme, (2014) Draft genome sequence of the filamentous cyanobacterium Leptolyngbya sp. strain Heron Island J, exhibiting chromatic acclimation. Genome Announcements 2(1): e01166-13.

DOI: 10.1128/genomea.01166-13.

Journal article.

Tarakeshwar, P., J.L. Palma, G.P. Holland, P. Fromme, J.L. Yarger, and V. Mujica, (2014) Probing the Nature of Charge Transfer at Nano–Bio Interfaces: Peptides on Metal Oxide Nanoparticles. The Journal of Physical Chemistry Letters,5(20): 3555-3559.

DOI: 10.1021/jz501854x.

Journal article.

Tenboer, J., S. Basu, N. Zatsepin, K. Pande, D. Milathianaki, M. Frank, M. Hunter, S. Boutet, G.J. Williams, J.E. Koglin, D. Oberthuer, M. Heymann, C. Kupitz, C. Conrad, J. Coe, S. Roy-Chowdhury, U. Weierstall, D. James, D. Wang, T. Grant, A. Barty, O. Yefanov, J. Scales, C. Gati, C. Seuring, V. Srajer, R. Henning, P. Schwander, R. Fromme, A. Ourmazd, K. Moffat, J.J. Van Thor, J.C.H. Spence, P. Fromme, H.N. Chapman, and M. Schmidt, (2014) Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein. Science, 346(6214): 1242-1246.

DOI: 10.1126/science.1259357.

Journal article.

Weierstall, U., D. James, C. Wang, T.A. White, D. Wang, W. Liu, J.C.H. Spence, R. Bruce Doak, G. Nelson, P. Fromme, R. Fromme, I. Grotjohann, C. Kupitz, N.A. Zatsepin, H. Liu, S. Basu, D. Wacker, G. Won Han, V. Katritch, S. Boutet, M. Messerschmidt, G.J. Williams, J.E. Koglin, M. Marvin Seibert, M. Klinker, C. Gati, R.L. Shoeman, A. Barty, H.N. Chapman, R.A. Kirian, K.R. Beyerlein, R.C. Stevens, D. Li, S.T.A. Shah, N. Howe, M. Caffrey, and V. Cherezov, (2014) Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nature Communications, 5: 3309.

DOI: 10.1038/ncomms4309.

Journal article.


2013

Abdallah, B.G., C. Kupitz, P. Fromme, and A. Ros, (2013) Crystallization of the Large Membrane Protein Complex Photosystem I in a Microfluidic Channel. ACS Nano, 7(12): 10534-10543.

DOI: 10.1021/nn402515q.

Journal article.

Abdallah, B.G., T.-C. Chao, C. Kupitz, P. Fromme, and A. Ros, (2013) Dielectrophoretic Sorting of Membrane Protein Nanocrystals. ACS Nano, 7(10): 9129-9137.

DOI: 10.1021/nn403760q.

Journal article.

Flory, J.D., S. Shinde, S. Lin, Y. Liu, H. Yan, G. Ghirlanda, and P. Fromme, (2013) PNA-Peptide Assembly in a 3D DNA Nanocage at Room Temperature. Journal of the American Chemical Society,  135(18): 6985-6993.

DOI: 10.1021/ja400762c.

Journal article.

Johansson, L.C., D. Arnlund, G. Katona, T.A. White, A. Barty, D.P. DePonte, R.L. Shoeman, C. Wickstrand, A. Sharma, G.J. Williams, A. Aquila, M.J. Bogan, C. Caleman, J. Davidsson, R.B. Doak, M. Frank, R. Fromme, L. Galli, I. Grotjohann, M.S. Hunter, S. Kassemeyer, R.A. Kirian, C. Kupitz, M. Liang, L. Lomb, E. Malmerberg, A.V. Martin, M. Messerschmidt, K. Nass, L. Redecke, M.M. Seibert, J. Sjöhamn, J. Steinbrener, F. Stellato, D. Wang, W.Y. Wahlgren, U. Weierstall, S. Westenhoff, N.A. Zatsepin, S. Boutet, J.C.H. Spence, I. Schlichting, H.N. Chapman, P. Fromme, and R. Neutze, (2013)  Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography. Nature Communications, 4: 2911.

DOI: 10.1038/ncomms3911.

Journal article.

Liu, W., D. Wacker, C. Gati, G.W. Han, D. James, D. Wang, G. Nelson, U. Weierstall, V. Katritch, A. Barty, N.A. Zatsepin, D. Li, M. Messerschmidt, S. Boutet, G.J. Williams, J.E. Koglin, M.M. Seibert, C. Wang, S.T.A. Shah, S. Basu, R. Fromme, C. Kupitz, K.N. Rendek, I. Grotjohann, P. Fromme, R.A. Kirian, K.R. Beyerlein, T.A. White, H.N. Chapman, M. Caffrey, J.C.H. Spence, R.C. Stevens, and V. Cherezov, (2013) Serial Femtosecond Crystallography of G Protein–Coupled Receptors. Science, 342(6165): 1521-1524.

DOI: 10.1126/science.1244142.

Journal article.

Pieper, U., A. Schlessinger, E. Kloppmann, G.A. Chang, J.J. Chou, M.E. Dumont, B.G. Fox, P. Fromme, W.A. Hendrickson, M.G. Malkowski, D.C. Rees, D.L. Stokes, M.H.B. Stowell, M.C. Wiener, B. Rost, R.M. Stroud, R.C. Stevens, and A. Sali, (2013) Coordinating the impact of structural genomics on the human [alpha]-helical transmembrane proteome. Nature Structural Molecular Biology,  20(2): 135-138.

DOI: 10.1038/nsmb.2508.

Journal article.

Redecke, L., K. Nass, D.P. DePonte, T.A. White, D. Rehders, A. Barty, F. Stellato, M. Liang, T.R.M. Barends, S. Boutet, G.J. Williams, M. Messerschmidt, M.M. Seibert, A. Aquila, D. Arnlund, S. Bajt, T. Barth, M.J. Bogan, C. Caleman, T.-C. Chao, R.B. Doak, H. Fleckenstein, M. Frank, R. Fromme, L. Galli, I. Grotjohann, M.S. Hunter, L.C. Johansson, S. Kassemeyer, G. Katona, R.A. Kirian, R. Koopmann, C. Kupitz, L. Lomb, A.V. Martin, S. Mogk, R. Neutze, R.L. Shoeman, J. Steinbrener, N. Timneanu, D. Wang, U. Weierstall, N.A. Zatsepin, J.C.H. Spence, P. Fromme, I. Schlichting, M. Duszenko, C. Betzel, and H.N. Chapman, (2013) Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser. Science, 339(6116): 227-230.

DOI: 10.1126/science.1229663.

Journal article.

Rendek, K.N., R. Fromme, I. Grotjohann, and P. Fromme, (2013) Crystallization of a self-assembled three-dimensional DNA nanostructure. Acta Crystallographica Section F, 69(2): 141-146.

DOI: 10.1107/S1744309112052128.

Journal article.

Zook, J.D., T.R. Molugu, N.E. Jacobsen, G. Lin, J. Soll, B.R. Cherry, M.F. Brown, and P. Fromme, (2013) High-Resolution NMR Reveals Secondary Structure and Folding of Amino Acid Transporter from Outer Chloroplast Membrane. PLoS ONE, 8(10): e78116.

DOI: 10.1371/journal.pone.0078116.

Journal article.


2012

Aquila, A., M.S. Hunter, R.B. Doak, R.A. Kirian, P. Fromme, T.A. White, J. Andreasson, D. Arnlund, S.a. Bajt, T.R.M. Barends, M. Barthelmess, M.J. Bogan, C. Bostedt, H. Bottin, J.D. Bozek, C. Caleman, N. Coppola, J. Davidsson, D.P. DePonte, V. Elser, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, M. Frank, R. Fromme, H. Graafsma, I. Grotjohann, L. Gumprecht, J. Hajdu, C.Y. Hampton, A. Hartmann, R. Hartmann, S. Hau-Riege, G. Hauser, H. Hirsemann, P. Holl, J.M. Holton, A. Hömke, L. Johansson, N. Kimmel, S. Kassemeyer, F. Krasniqi, K.-U. Kühnel, M. Liang, L. Lomb, E. Malmerberg, S. Marchesini, A.V. Martin, F.R.N.C. Maia, M. Messerschmidt, K. Nass, C. Reich, R. Neutze, D. Rolles, B. Rudek, A. Rudenko, I. Schlichting, C. Schmidt, K.E. Schmidt, J. Schulz, M.M. Seibert, R.L. Shoeman, R. Sierra, H. Soltau, D. Starodub, F. Stellato, S. Stern, L. Strüder, N. Timneanu, J. Ullrich, X. Wang, G.J. Williams, G. Weidenspointner, U. Weierstall, C. Wunderer, A. Barty, J.C.H. Spence, and H.N. Chapman, (2012) Time-resolved protein nanocrystallography using an X-ray free-electron laser. Optics Express, 20(3): 2706-2716.

DOI: 10.1364/OE.20.002706.

Journal article.

Barty, A., C. Caleman, A. Aquila, N. Timneanu, L. Lomb, T.A. White, J. Andreasson, D. Arnlund, S. Bajt, T.R.M. Barends, M. Barthelmess, M.J. Bogan, C. Bostedt, J.D. Bozek, R. Coffee, N. Coppola, J. Davidsson, D.P. DePonte, R.B. Doak, T. Ekeberg, V. Elser, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, P. Fromme, H. Graafsma, L. Gumprecht, J. Hajdu, C.Y. Hampton, R. Hartmann, A. Hartmann, G. Hauser, H. Hirsemann, P. Holl, M.S. Hunter, L. Johansson, S. Kassemeyer, N. Kimmel, R.A. Kirian, M. Liang, F.R.N.C. Maia, E. Malmerberg, S. Marchesini, A.V. Martin, K. Nass, R. Neutze, C. Reich, D. Rolles, B. Rudek, A. Rudenko, H. Scott, I. Schlichting, J. Schulz, M.M. Seibert, R.L. Shoeman, R.G. Sierra, H. Soltau, J.C.H. Spence, F. Stellato, S. Stern, L. Struder, J. Ullrich, WangX, G. Weidenspointner, U. Weierstall, C.B. Wunderer, and H.N. Chapman, (2012) Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Nature Photonics, 6(1):  35-40.

DOI: 10.1038/nphoton.2011.297.

Journal article.

Boutet, S., L. Lomb, G.J. Williams, T.R.M. Barends, A. Aquila, R.B. Doak, U. Weierstall, D.P. DePonte, J. Steinbrener, R.L. Shoeman, M. Messerschmidt, A. Barty, T.A. White, S. Kassemeyer, R.A. Kirian, M.M. Seibert, P.A. Montanez, C. Kenney, R. Herbst, P. Hart, J. Pines, G. Haller, S.M. Gruner, H.T. Philipp, M.W. Tate, M. Hromalik, L.J. Koerner, N. van Bakel, J. Morse, W. Ghonsalves, D. Arnlund, M.J. Bogan, C. Caleman, R. Fromme, C.Y. Hampton, M.S. Hunter, L.C. Johansson, G. Katona, C. Kupitz, M. Liang, A.V. Martin, K. Nass, L. Redecke, F. Stellato, N. Timneanu, D. Wang, N.A. Zatsepin, D. Schafer, J. Defever, R. Neutze, P. Fromme, J.C.H. Spence, H.N. Chapman, and I. Schlichting, (2012) High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography. Science,  337(6092): 362-364.

DOI: 10.1126/science.1217737.

Journal article.

Brunger, Axel T., Paul D. Adams, P. Fromme, R. Fromme, M. Levitt, and Gunnar F. Schröder, (2012) Improving the Accuracy of Macromolecular Structure Refinement at 7 Å Resolution. Structure,  20(6): 957-966.

DOI: 10.1016/j.str.2012.04.020.

Journal article.

Johansson, L.C., D. Arnlund, T.A. White, G. Katona, D.P. DePonte, U. Weierstall, R.B. Doak, R.L. Shoeman, L. Lomb, E. Malmerberg, J. Davidsson, K. Nass, M. Liang, J. Andreasson, A. Aquila, S. Bajt, M. Barthelmess, A. Barty, M.J. Bogan, C. Bostedt, J.D. Bozek, C. Caleman, R. Coffee, N. Coppola, T. Ekeberg, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, H. Graafsma, L. Gumprecht, J. Hajdu, C.Y. Hampton, R. Hartmann, A. Hartmann, G. Hauser, H. Hirsemann, P. Holl, M.S. Hunter, S. Kassemeyer, N. Kimmel, R.A. Kirian, F.R.N.C. Maia, S. Marchesini, A.V. Martin, C. Reich, D. Rolles, B. Rudek, A. Rudenko, I. Schlichting, J. Schulz, M.M. Seibert, R.G. Sierra, H. Soltau, D. Starodub, F. Stellato, S. Stern, L. Struder, N. Timneanu, J. Ullrich, W.Y. Wahlgren, X. Wang, G. Weidenspointner, C. Wunderer, P. Fromme, H.N. Chapman, J.C.H. Spence, and R. Neutze, (2012) Lipidic phase membrane protein serial femtosecond crystallography. Nature Methods,  9(3): 263-265.

DOI: 10.1038/nmeth.1867.

Journal article.

Koopmann, R., K. Cupelli, L. Redecke, K. Nass, D.P. DePonte, T.A. White, F. Stellato, D. Rehders, M. Liang, J. Andreasson, A. Aquila, S. Bajt, M. Barthelmess, A. Barty, M.J. Bogan, C. Bostedt, S. Boutet, J.D. Bozek, C. Caleman, N. Coppola, J. Davidsson, R.B. Doak, T. Ekeberg, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, H. Graafsma, L. Gumprecht, J. Hajdu, C.Y. Hampton, A. Hartmann, R. Hartmann, G. Hauser, H. Hirsemann, P. Holl, M.S. Hunter, S. Kassemeyer, R.A. Kirian, L. Lomb, F.R.N.C. Maia, N. Kimmel, A.V. Martin, M. Messerschmidt, C. Reich, D. Rolles, B. Rudek, A. Rudenko, I. Schlichting, J. Schulz, M.M. Seibert, R.L. Shoeman, R.G. Sierra, H. Soltau, S. Stern, L. Struder, N. Timneanu, J. Ullrich, X. Wang, G. Weidenspointner, U. Weierstall, G.J. Williams, C.B. Wunderer, P. Fromme, J.C.H. Spence, T. Stehle, H.N. Chapman, C. Betzel, and M. Duszenko, (2012) In vivo protein crystallization opens new routes in structural biology. Nature Methods,  9(3): 259-262.

DOI: 10.1038/nmeth.1859.

Journal article.


2011

Chapman, H.N., P. Fromme, A. Barty, T.A. White, R.A. Kirian, A. Aquila, M.S. Hunter, J. Schulz, D.P. DePonte, U. Weierstall, R.B. Doak, F.R.N.C. Maia, A.V. Martin, I. Schlichting, L. Lomb, N. Coppola, R.L. Shoeman, S.W. Epp, R. Hartmann, D. Rolles, A. Rudenko, L. Foucar, N. Kimmel, G. Weidenspointner, P. Holl, M. Liang, M. Barthelmess, C. Caleman, S. Boutet, M.J. Bogan, J. Krzywinski, C. Bostedt, S. Bajt, L. Gumprecht, B. Rudek, B. Erk, C. Schmidt, A. Homke, C. Reich, D. Pietschner, L. Struder, G. Hauser, H. Gorke, J. Ullrich, S. Herrmann, G. Schaller, F. Schopper, H. Soltau, K.-U. Kuhnel, M. Messerschmidt, J.D. Bozek, S.P. Hau-Riege, M. Frank, C.Y. Hampton, R.G. Sierra, D. Starodub, G.J. Williams, J. Hajdu, N. Timneanu, M.M. Seibert, J. Andreasson, A. Rocker, O. Jonsson, M. Svenda, S. Stern, K. Nass, R. Andritschke, C.-D. Schroter, F. Krasniqi, M. Bott, K.E. Schmidt, X. Wang, I. Grotjohann, J.M. Holton, T.R.M. Barends, R. Neutze, S. Marchesini, R. Fromme, S. Schorb, D. Rupp, M. Adolph, T. Gorkhover, I. Andersson, H. Hirsemann, G. Potdevin, H. Graafsma, B. Nilsson, and J.C.H. Spence, (2011) Femtosecond X-ray protein nanocrystallography. Nature, 470(7332): 73-77.

DOI: 10.1038/nature09750.

Journal article.

Chauhan, D., I.M. Folea, C.C. Jolley, R. Kouřil, C.E. Lubner, S. Lin, D. Kolber, F. Wolfe-Simon, J.H. Golbeck, E.J. Boekema, and P. Fromme, (2011) A Novel Photosynthetic Strategy for Adaptation to Low-Iron Aquatic Environments. Biochemistry, 50(5): 686-692.

DOI: 10.1021/bi1009425.

Journal article.

Fromme, P. and J.C.H. Spence, (2011) Femtosecond nanocrystallography using X-ray lasers for membrane protein structure determination. Current Opinion in Structural Biology, 21(4): 509-516.

DOI: 10.1016/j.sbi.2011.06.001.

Journal article.

Hunter, M.S. and P. Fromme, (2011) Toward structure determination using membrane–protein nanocrystals and microcrystals. Methods, 55(4): 387-404.

DOI: 10.1016/j.ymeth.2011.12.006.

Journal article.

Hunter, M.S., D.P. DePonte, D.A. Shapiro, R.A. Kirian, X. Wang, D. Starodub, S. Marchesini, U. Weierstall, R.B. Doak, J.C.H. Spence, and P. Fromme, (2011) X-ray Diffraction from Membrane Protein Nanocrystals. Biophysical Journal,100(1): 198-206.

DOI: 10.1016/j.bpj.2010.10.049.

Journal article.

Kirian, R.A., T.A. White, J.M. Holton, H.N. Chapman, P. Fromme, A. Barty, L. Lomb, A. Aquila, F.R.N.C. Maia, A.V. Martin, R. Fromme, X. Wang, M.S. Hunter, K.E. Schmidt, and J.C.H. Spence, (2011) Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals. Acta Crystallographica Section A: Foundations of Crystallography, 67(Part 2): 131-140.

DOI: 10.1107/S0108767310050981.

Journal article.

Lawrence, R.M., B. Varco-Merth, C.J. Bley, J.J.L. Chen, and P. Fromme, (2011) Recombinant production and purification of the subunit c of chloroplast ATP synthase. Protein expression and purification, 76(1): 15-24.

DOI: 10.1016/j.pep.2010.10.009.

Journal article.

Lomb, L., T.R.M. Barends, S. Kassemeyer, A. Aquila, S.W. Epp, B. Erk, L. Foucar, R. Hartmann, B. Rudek, D. Rolles, A. Rudenko, R.L. Shoeman, J. Andreasson, S. Bajt, M. Barthelmess, A. Barty, M.J. Bogan, C. Bostedt, J.D. Bozek, C. Caleman, R. Coffee, N. Coppola, D.P. DePonte, R.B. Doak, T. Ekeberg, H. Fleckenstein, P. Fromme, M. Gebhardt, H. Graafsma, L. Gumprecht, C.Y. Hampton, A. Hartmann, G. Hauser, H. Hirsemann, P. Holl, J.M. Holton, M.S. Hunter, W. Kabsch, N. Kimmel, R.A. Kirian, M. Liang, F.R.N.C. Maia, A. Meinhart, S. Marchesini, A.V. Martin, K. Nass, C. Reich, J. Schulz, M.M. Seibert, R. Sierra, H. Soltau, J.C.H. Spence, J. Steinbrener, F. Stellato, S. Stern, N. Timneanu, X. Wang, G. Weidenspointner, U. Weierstall, T.A. White, C. Wunderer, H.N. Chapman, J. Ullrich, L. Strüder, and I. Schlichting, (2011) Radiation damage in protein serial femtosecond crystallography using an X-ray free-electron laser. Physical Review B, 84(21): 214111.

DOI: 10.1103/PhysRevB.84.214111.

Journal article.

Ni, D.Q., J. Zook, D.A. Klewer, R.A. Nieman, J. Soll, and P. Fromme, (2011) Isolation, folding and structural investigations of the amino acid transporter OEP16. Protein expression and purification, 80(2): 157-168.

DOI: 10.1016/j.pep.2011.08.004.

Journal article.

Seibert, M.M., T. Ekeberg, F.R.N.C. Maia, M. Svenda, J. Andreasson, O. Jonsson, D. Odic, B. Iwan, A. Rocker, D. Westphal, M. Hantke, D.P. DePonte, A. Barty, J. Schulz, L. Gumprecht, N. Coppola, A. Aquila, M. Liang, T.A. White, A. Martin, C. Caleman, S. Stern, C. Abergel, V. Seltzer, J.-M. Claverie, C. Bostedt, J.D. Bozek, S. Boutet, A.A. Miahnahri, M. Messerschmidt, J. Krzywinski, G. Williams, K.O. Hodgson, M.J. Bogan, C.Y. Hampton, R.G. Sierra, D. Starodub, I. Andersson, S. Bajt, M. Barthelmess, J.C.H. Spence, P. Fromme, U. Weierstall, R. Kirian, M. Hunter, R.B. Doak, S. Marchesini, S.P. Hau-Riege, M. Frank, R.L. Shoeman, L. Lomb, S.W. Epp, R. Hartmann, D. Rolles, A. Rudenko, C. Schmidt, L. Foucar, N. Kimmel, P. Holl, B. Rudek, B. Erk, A. Homke, C. Reich, D. Pietschner, G. Weidenspointner, L. Struder, G. Hauser, H. Gorke, J. Ullrich, I. Schlichting, S. Herrmann, G. Schaller, F. Schopper, H. Soltau, K.-U. Kuhnel, R. Andritschke, C.-D. Schroter, F. Krasniqi, M. Bott, S. Schorb, D. Rupp, M. Adolph, T. Gorkhover, H. Hirsemann, G. Potdevin, H. Graafsma, B. Nilsson, H.N. Chapman, and J. Hajdu, (2011) Single mimivirus particles intercepted and imaged with an X-ray laser. Nature, 470(7332): 78-81.

DOI: 10.1038/nature09748.

Journal article.

Thangaraj, B., C.C. Jolley, I. Sarrou, J.B. Bultema, J. Greyslak, J.P. Whitelegge, S. Lin, R. Kouřil, R. Subramanyam, E.J. Boekema, and P. Fromme, (2011) Efficient Light Harvesting in a Dark, Hot, Acidic Environment: The Structure and Function of PSI-LHCI from Galdieria sulphuraria. Biophysical Journal, 100(1): 135-143.

DOI: 10.1016/j.bpj.2010.09.069.

Journal article.


2010

Kirian, R.A., X. Wang, U. Weierstall, K.E. Schmidt, J.C.H. Spence, M. Hunter, P. Fromme, T. White, H.N. Chapman, and J. Holton, (2010) Femtosecond protein nanocrystallography—data analysis methods. Optics Express, 18(6): 5713-5723.

DOI: 10.1364/OE.18.005713.

Journal article.

Subramanyam, R., C. Jolley, B. Thangaraj, S. Nellaepalli, A.N. Webber, and P. Fromme, (2010) Structural and functional changes of PSI-LHCI supercomplexes of Chlamydomonas reinhardtii cells grown under high salt conditions. Planta, 231(4): 913-922.

DOI: 10.1007/s00425-009-1097-x.

Journal article.

Thangaraj, B., C.M. Ryan, P. Souda, K. Krause, K.F. Faull, A.P.M. Weber, P. Fromme, and J.P. Whitelegge, (2010) Data‐directed top‐down Fourier‐transform mass spectrometry of a large integral membrane protein complex: Photosystem II from Galdieria sulphuraria. Proteomics, 10(20): 3644-3656.

DOI: 10.1002/pmic.201000190.

Journal article.


2009

Vanselow, C., A.P.M. Weber, K. Krause, and P. Fromme, (2009) Genetic analysis of the Photosystem I subunits from the red alga, Galdieria sulphuraria. Biochimica et Biophysica Acta (BBA) – Bioenergetics,  1787(1): 46-59.

DOI: 10.1016/j.bbabio.2008.10.004.

Journal article.

Xin, Y., Y.-K. Lu, R. Fromme, P. Fromme, and R.E. Blankenship, (2009) Purification, characterization and crystallization of menaquinol: fumarate oxidoreductase from the green filamentous photosynthetic bacterium Chloroflexus aurantiacus. Biochimica et Biophysica Acta (BBA)-Bioenergetics,  1787(2): 86-96.

DOI: 10.1016/j.bbabio.2008.11.010.

Journal article.


2008

Fromme, R., Z. Katiliene, P. Fromme, and G. Ghirlanda, (2008) Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 Å resolution. Protein Science, 17(5): 939-944.

DOI: 10.1110/ps.083472808.

Journal article.

Jolley, C.C., S.A. Wells, P. Fromme, and M.F. Thorpe, (2008) Fitting Low-Resolution Cryo-EM Maps of Proteins Using Constrained Geometric Simulations. Biophysical Journal, 94(5): 1613-1621.

DOI: 10.1529/biophysj.107.115949.

Journal article.

Shapiro, D.A., H.N. Chapman, D. DePonte, R.B. Doak, P. Fromme, G. Hembree, M. Hunter, S. Marchesini, K. Schmidt, J. Spence, D. Starodub, and U. Weierstall, (2008) Powder diffraction from a continuous microjet of submicrometer protein crystals. Journal of Synchrotron Radiation, 15(6): 593-599.

DOI: 10.1107/S0909049508024151.

Journal article.

Starodub, D., P. Rez, G. Hembree, M. Howells, D. Shapiro, H.N. Chapman, P. Fromme, K. Schmidt, U. Weierstall, R.B. Doak, and J.C.H. Spence, (2008) Dose, exposure time and resolution in serial X-ray crystallography. Journal of synchrotron radiation, 15(1): 62-73.

DOI: 10.1107/S0909049507048893.

Journal article.

Varco-Merth, B., R. Fromme, M. Wang, and P. Fromme, (2008) Crystallization of the c14-rotor of the chloroplast ATP synthase reveals that it contains pigments. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1777(7): 605-612.

DOI: 10.1016/j.bbabio.2008.05.009.

Journal article.

Weierstall, U., R.B. Doak, J.C.H. Spence, D. Starodub, D. Shapiro, P. Kennedy, J. Warner, G.G. Hembree, P. Fromme, and H.N. Chapman, (2008) Droplet streams for serial crystallography of proteins. Experiments in Fluids, 44(5): 675-689.

DOI: 10.1007/s00348-007-0426-8.

Journal article.


2007

Fromme, R., Z. Katiliene, B. Giomarelli, F. Bogani, J. Mc Mahon, T. Mori, P. Fromme, and G. Ghirlanda, (2007) A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity. Biochemistry, 46(32): 9199-9207.

DOI: 10.1021/bi700666m.

Journal article.

Riley, K.J., T. Reinot, R. Jankowiak, P. Fromme, and V. Zazubovich, (2007) Red antenna states of photosystem I from cyanobacteria Synechocystis PCC 6803 and Thermosynechococcus elongatus: Single-complex spectroscopy and spectral hole-burning study. The Journal of Physical Chemistry B, 111(1): 286-292.

DOI: 10.1021/jp062664m.

Journal article.


2006

Fromme, P., H.Q. Yu, Y.S. DeRuyter, C. Jolley, D.K. Chauhan, A. Melkozernov, and I. Grotjohann, (2006) Structure of photosystems I and II. Comptes Rendus Chimie, 9(2): 188-200.

DOI: 10.1016/j.crci.2005.06.039.

Journal article.

Jolley, C.C., S.A. Wells, B.M. Hespenheide, M.F. Thorpe, and P. Fromme, (2006) Docking of Photosystem I Subunit C Using a Constrained Geometric Simulation. Journal of the American Chemical Society, 128(27): 8803-8812.

DOI: 10.1021/ja0587749.

Journal article.

Subramanyam, R., C. Jolley, D.C. Brune, P. Fromme, and A.N. Webber, (2006) Characterization of a novel Photosystem I–LHCI supercomplex isolated from Chlamydomonas reinhardtii under anaerobic (State II) conditions. FEBS Letters, 580(1): 233-238.

DOI: 10.1016/j.febslet.2005.12.003.

Journal article.

Vaswani, H.M., J. Stenger, P. Fromme, and G.R. Fleming, (2006) One- and Two-Color Photon Echo Peak Shift Studies of Photosystem I. The Journal of Physical Chemistry B, 110(51): 26303-26312.

DOI: 10.1021/jp061008j.

Journal article.


2005

Grotjohann, I. and P. Fromme, (2005) Structure of cyanobacterial Photosystem I. Photosynthesis Research, 85(1): 51-72.

DOI: 10.1007/s11120-005-1440-4.

Journal article.

Jolley, C., A. Ben-Shem, N. Nelson, and P. Fromme, (2005) Structure of Plant Photosystem I Revealed by Theoretical Modeling. Journal of Biological Chemistry,280(39): 33627-33636.

DOI: 10.1074/jbc.m500937200.

Journal article.

Şener, M.K., C. Jolley, A. Ben-Shem, P. Fromme, N. Nelson, R. Croce, and K. Schulten, (2005) Comparison of the Light-Harvesting Networks of Plant and Cyanobacterial Photosystem I. Biophysical Journal, 89(3): 1630-1642.

DOI: 10.1529.

Journal article.

Spence, J.C.H., K. Schmidt, J.S. Wu, G. Hembree, U. Weierstall, B. Doak, and P. Fromme, (2005) Diffraction and imaging from a beam of laser-aligned proteins: resolution limits. Acta Crystallographica Section A: Foundations of Crystallography,  61(2): 237-245.

DOI: 10.1107/s0108767305002710.

Journal article.


2004

Chayen, N., M. Dieckmann, K. Dierks, and P. Fromme, (2004) Size and shape determination of proteins in solution by a noninvasive depolarized dynamic light scattering instrument. Annals of the New York Academy of Sciences, 1027(1): 20-27.

DOI: 10.1196/annals.1324.003.

Journal article.

Fromme, P. and P. Mathis, (2004) Unraveling the Photosystem I reaction center: a history, or the sum of many efforts. Photosynthesis Research,  80(1-3): 109-124.

DOI: 10.1023/b:pres.0000030657.88242.e1.

Journal article.

Grotjohann, I., C. Jolley, and P. Fromme, (2004) Evolution of photosynthesis and oxygen evolution: Implications from the structural comparison of Photosystems I and II. Physical Chemistry Chemical Physics, 6(20): 4743-4753.

DOI: 10.1039/B408980D.

Journal article.

Linke, D., J. Frank, M.S. Pope, J. Soll, I. Ilkavets, P. Fromme, E.A. Burstein, Y.K. Reshetnyak, and V.I. Emelyanenko, (2004) Folding kinetics and structure of OEP16. Biophysical journal,  86(3): 1479-1487.

DOI: 10.1016.

Journal article.

Şener, M.K., S. Park, D. Lu, A. Damjanović, T. Ritz, P. Fromme, and K. Schulten, (2004) Excitation migration in trimeric cyanobacterial photosystem I. The Journal of chemical physics, 120(23): 11183-11195.

DOI: 10.1063/1.1739400.

Journal article.


2003

Antonkine, M.L., P. Jordan, P. Fromme, N. Krauß, J.H. Golbeck, and D. Stehlik, (2003) Assembly of protein subunits within the stromal ridge of photosystem I. Structural changes between unbound and sequentially PS I-bound polypeptides and correlated changes of the magnetic properties of the terminal iron sulfur clusters. Journal of molecular biology, 327(3): 671-697.

DOI: 10.1016/s0022-2836(03)00145-1.

Journal article.

Fromme, P., A. Melkozernov, P. Jordan, and N. Krauss, (2003) Structure and function of photosystem I: interaction with its soluble electron carriers and external antenna systems. FEBS letters, 555(1): 40-44.

DOI: 10.1016/s0014-5793(03)01124-4.

Journal article.

Plato, M., N. Krauß, P. Fromme, and W. Lubitz, (2003) Molecular orbital study of the primary electron donor P700 of photosystem I based on a recent X-ray single crystal structure analysis. Chemical physics, 294(3): 483-499.

DOI: 10.1016/S0301-0104(03)00378-1.

Journal article.


2002

Balaban, T.S., P. Fromme, A.R. Holzwarth, N. Krauß, and V.I. Prokhorenko, (2002) Relevance of the diastereotopic ligation of magnesium atoms of chlorophylls in Photosystem I. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1556(2): 197-207.

DOI: 10.1016/s0005-2728(02)00363-8.

Journal article.

Byrdin, M., P. Jordan, N. Krauss, P. Fromme, D. Stehlik, and E. Schlodder, (2002) Light Harvesting in Photosystem I: Modeling Based on the 2.5-Å Structure of Photosystem I from Synechococcus elongatus. Biophysical journal, 83(1): 433-457

DOI: 10.1016/S0006-3495(02)75181-3.

Journal article.

Damjanovic, A., H.M. Vaswani, P. Fromme, and G.R. Fleming, (2002) Chlorophyll excitations in photosystem I of Synechococcus elongatus. The Journal of Physical Chemistry B, 106(39): 10251-10262.

DOI: 10.1021/jp020963f.

Journal article.

Fromme, P., H. Bottin, N. Krauss, and P. Sétif, (2002) Crystallization and Electron Paramagnetic Resonance Characterization of the Complex of Photosystem I with its Natural Electron Acceptor Ferredoxin. Biophysical Journal, 83(4): 1760-1773.

DOI: 10.1016.

Journal article.

Fromme, P., J. Kern, B. Loll, J. Biesiadka, W. Saenger, H.T. Witt, N. Krauss, and A. Zouni, (2002) Functional implications on the mechanism of the function of photosystem II including water oxidation based on the structure of photosystem II. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 357(1426): 1337-1345.

DOI: 10.1098.

Journal article.

Sener, M.K., D. Lu, T. Ritz, S. Park, P. Fromme, and K. Schulten, (2002) Robustness and optimality of light harvesting in cyanobacterial photosystem I. The Journal of Physical Chemistry B, 106(32): 7948-7960.

DOI: 10.1021/jp020708v.

Journal article.


2001

Fromme, P., P. Jordan, and N. Krauß, (2001) Structure of photosystem I. Biochimica et Biophysica Acta (BBA) – Bioenergetics, 1507(1–3): 5-31

DOI: 10.1016/S0005-2728(01)00195-5.

Journal article.

Hofbauer, W., A. Zouni, R. Bittl, J. Kern, P. Orth, F. Lendzian, P. Fromme, H.T. Witt, and W. Lubitz, (2001) Photosystem II single crystals studied by EPR spectroscopy at 94 GHz: The tyrosine radical YD. Proceedings of the National Academy of Sciences,  98(12): 6623-6628.

DOI: 10.1073/pnas.101127598.

Journal article.

Jordan, P., P. Fromme, H.T. Witt, O. Klukas, W. Saenger, and N. Krauß, (2001) Three-dimensional structure of cyanobacterial photosystem I at 2.5 Å resolution. Nature,  411(6840): 909-917.

DOI: 10.1038/35082000.

Journal article.

Käss, H., P. Fromme, H.T. Witt, and W. Lubitz, (2001) Orientation and electronic structure of the primary donor radical cation in photosystem I: A single crystals EPR and ENDOR study. The Journal of Physical Chemistry B, 105(6): 1225-1239.

DOI: 10.1021/jp0032311.

Journal article.

Zouni, A., H.-T. Witt, J. Kern, P. Fromme, N. Krauss, W. Saenger, and P. Orth, (2001) Crystal structure of photosystem II from Synechococcus elongatus at 3.8 A resolution. Nature,  409(6821): 39-743.

DOI: 10.1038/35055589.

Journal article.


2000

Linke, D., J. Frank, J.F. Holzwarth, J. Soll, C. Boettcher, and P. Fromme, (2000) In vitro reconstitution and biophysical characterization of OEP16, an outer envelope pore protein of pea chloroplasts. Biochemistry, 39(36): 11050-11056.

DOI: 10.1021/bi001034m.

Journal article.

Zech, S.G., W. Hofbauer, A. Kamlowski, P. Fromme, D. Stehlik, W. Lubitz, and R. Bittl, (2000) A structural model for the charge separated state P700+A1- in Photosystem I from the orientation of the magnetic interaction tensors. The Journal of Physical Chemistry B, 104(41): 9728-9739.

DOI: 10.1021/jp002125w.

Journal article.

Zouni, A., R. Jordan, E. Schlodder, P. Fromme, and H.T. Witt, (2000) First photosystem II crystals capable of water oxidation. Biochimica et Biophysica Acta (BBA)-Bioenergetics,  1457(3): 103-105.

DOI: 10.1016/S0005-2728(00)00100-6.

Journal article.


1999

Klukas, O., W.-D. Schubert, P. Jordan, N. Krauß, P. Fromme, H.T. Witt, and W. Saenger, (1999) Localization of two phylloquinones, QK and QK′, in an improved electron density map of photosystem I at 4-Å resolution. Journal of Biological Chemistry, 274(11): 7361-7367.

DOI: 10.1074/jbc.274.11.7361.

Journal article.

Klukas, O., W.-D. Schubert, P. Jordan, N. Krauß, P. Fromme, H.T. Witt, and W. Saenger, (1999) Photosystem I, an improved model of the stromal subunits PsaC, PsaD, and PsaE. Journal of Biological Chemistry,  274(11): 7351-7360.

DOI: 10.1074/jbc.274.11.7351.

Journal article.


1998

Fromme, P. and H.T. Witt, (1998) Improved isolation and crystallization of photosystem I for structural analysis. Biochimica et Biophysica Acta (BBA) – Bioenergetics, 1365(1–2): 175-184.

DOI: 10.1016/S0005-2728(98)00059-0.

Journal article.

Kamlowski, A., B. Altenberg-Greulich, A. van der Est, S.G. Zech, R. Bittl, P. Fromme, W. Lubitz, and D. Stehlik, (1998) The quinone acceptor A1 in Photosystem I: Binding site, and comparison to QA in purple bacteria reaction centers. The Journal of Physical Chemistry B, 102(42):  8278-8287.

DOI: 10.1021/jp9824611.

Journal article.

Kamlowski, A., S.G. Zech, P. Fromme, R. Bittl, W. Lubitz, H.T. Witt, and D. Stehlik, (1998) The Radical Pair State in Photosystem I Single Crystals: Orientation Dependence of the Transient Spin-Polarized EPR Spectra. The Journal of Physical Chemistry B, 102(42): 8266-8277.

DOI: 10.1021/jp9817022.

Journal article.

Schubert, W.-D., O. Klukas, W. Saenger, H.T. Witt, P. Fromme, and N. Krauß, (1998) A common ancestor for oxygenic and anoxygenic photosynthetic systems: A comparison based on the structural model of photosystem I. Journal of molecular biology, 280(2): 297-314.

DOI: 10.1006/jmbi.1998.1824.

Journal article.


1997

Bittl, R., S.G. Zech, P. Fromme, H.T. Witt, and W. Lubitz, (1997) Pulsed EPR structure analysis of photosystem I single crystals: localization of the phylloquinone acceptor. Biochemistry,  36(40): 12001-12004.

DOI: 10.1021/bi971645n.

Journal article.

Kamlowski, A., A. van der Est, P. Fromme, and D. Stehlik, (1997) Low temperature EPR on Photosystem I single crystals: orientation of the iron–sulfur centers FA and FB. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1319(2): 185-198.

DOI: 10.1016/S0005-2728(96)00161-2.

Journal article.

Kamlowski, A., A. van der Est, P. Fromme, N. Krauß, W.-D. Schubert, O. Klukas, and D. Stehlik, (1997) The structural organization of the PsaC protein in Photosystem I from single crystal EPR and X-ray crystallographic studies. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1319(2): 199-213.

DOI: 10.1016/S0005-2728(96)00162-4.

Journal article.

Schubert, W.-D., O. Klukas, N. Krauß, W. Saenger, P. Fromme, and H.T. Witt, (1997) Photosystem I of Synechococcus elongatus at 4 Å resolution: comprehensive structure analysis. Journal of molecular biology, 272(5): 741-769.

DOI: 10.1006/jmbi.1997.1269.

Journal article.

van der Est, A., T. Prisner, R. Bittl, P. Fromme, W. Lubitz, K. Mobius, and D. Stehlik, (1997) Time-Resolved X-, K-, and W-Band EPR of the Radical Pair State P.-700A. 1 of Photosystem I in Comparison with P.+ 865Q.-A in Bacterial Reaction Centers. Journal of Physical Chemistry, 101(8): 1437-1443.

DOI: 10.1021/jp9622086.

Journal article.


1996

Fromme, P., (1996) Structure and function of photosystem I. Current opinion in structural biology, 6(4): 473-484

DOI: 10.1016/S0959-440X(96)80112-6.

Journal article.

Fromme, P., H.T. Witt, W.-D. Schubert, O. Klukas, W. Saenger, and N. Krauβ, (1996) Structure of Photosystem I at 4.5 Å resolution: a short review including evolutionary aspects. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1275(1): 76-83.

DOI: 10.1016/0005-2728(96)00053-9.

Journal article.

Jekow, P., W.-D. Schubert, P. Fromme, J. Kruip, P.R. Chitnis, M. Rögner, and W. Saenger, (1996) Crystallization of Intact and Subunit L-Deficient Monomers from Synechocystis PCC 6803 Photosystem I. Z. Naturforsch. C, 51(3-4): 195-199.

DOI: 10.1515/znc-1996-3-410.

Journal article.

Käβ, H., P. Fromme, and W. Lubitz, (1996) Quadrupole parameters of nitrogen nuclei in the cation radical P700.+ determined by ESEEM of single crystals of phtosystem I. Chemical Physics Letters, 257(1–2): 197-206.

DOI: 10.1016/0009-2614(96)00533-7.

Journal article.

Krauß, N., W.-D. Schubert, O. Klukas, P. Fromme, H.T. Witt, and W. Saenger, (1996) Photosystem I at 4 Å resolution represents the first structural model of a joint photosynthetic reaction centre and core antenna system. Nat Struct Mol Biol, 3(11): 965-973

DOI: 10.1038/nsb1196-965.

Journal article.


1995

Jekow, P., P. Fromme, H.T. Witt, and W. Saenger, (1995) Photosystem I from Synechococcus elongatus: preparation and crystallization of monomers with varying subunit compositions. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1229(1): 115-120.

DOI: 10.1016/0005-2728(94)00201-F.

Journal article.


1994

Fromme, P., W.-D. Schubert, and N. Krauß, (1994) Structure of Photosystem I: Suggestions on the docking sites for plastocyanin, ferredoxin and the coordination of P700. Biochimica et Biophysica Acta (BBA) – Bioenergetics, 1187(2): 99-105.

DOI: 10.1016/0005-2728(94)90092-2.

Journal article.

Kuhn, M., P. Fromme, and L. Krabben, (1994) A ‘membrane attached’ alpha-helix: a conserved structural motif in bacterial reaction centres, photosystem I and chloroplast NADH-plastoquinone oxidoreductase. Trends in Biochemical Sciences, 19(10): 401-402.

DOI: 10.1016/0968-0004(94)90085-X.

Journal article.


1993

Krauß, N., W. Hinrichs, I. Witt, P. Fromme, W. Pritzkow, Z. Dauter, C. Betzel, K.S. Wilson, H.T. Witt, and W. Saenger, (1993) Three-dimensional structure of system I of photosynthesis at 6 Å resolution. Nature, 361(6410): 326-331.

DOI: 10.1038/361326a0.

Journal article.

Lüneberg, J., P. Fromme, P. Jekow, and E. Schlodder, (1994) Spectroscopic characterization of PS I core complexes from thermophilic Synechococcus sp: Identical reoxidation kinetics of A1- before and after removal of theiron-sulfur-clusters FA and FB. FEBS letters, 338(2): 197-202.

DOI: 10.1016/0014-5793(94)80364-1.

Journal article.


1992

Brettel, K., I. Sieckmann, P. Fromme, A. van der Est, and D. Stehlik, (1992) Low-temperature EPR on single crystals of photosystem I: study of the iron-sulfur center FA. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1098(2): 266-270.

DOI: 10.1016/S0005-2728(05)80346-9.

Journal article.

Fromme, P., I. Dahse, and P. Gräber, (1992) Effect of Tentoxin on the activation and on the catalytic reaction of reconstituted H+-ATPase from Chloroplasts. Z. Naturforsch., 47c: 239-244.

DOI: 10.1515/znc-1992-3-412.

Journal article.


1990

Fromme, P. and P. Gräber, (1990) Activation/inactivation and uni-site catalysis by the reconstituted ATP-synthase from chloroplasts. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1016(1): 29-42.

DOI: 10.1016/0005-2728(90)90003-M.

Journal article.

Fromme, P. and P. Gräber, (1990) ATP-hydrolysis in chloroplasts: uni-site catalysis and evidence for heterogeneity of catalytic sites. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1020(2): 187-194.

DOI: 10.1016/0005-2728(90)90050-E.

Journal article.

Fromme, P. and P. Gräber, (1990) Uni-site catalysis in thylakoids: The influence of membrane energization on ATP hydrolysis and ATP-Pi exchange. FEBS letters, 269(1): 247-251.

DOI: 10.1016/0014-5793(90)81165-K.

Journal article.

Gräber, P., P. Fromme, and U. Junesch, (1990) Uni-Site Catalysis by the Reconstituted ATP Synthase from Chloroplasts, in Current Research in Photosynthesis, M. Baltscheffsky, Editor. Springer: Netherlands. 1921-1927.

DOI: 10.1007/978-94-009-0511-5_441.

Book chapter.

Labahn, A., P. Fromme, and P. Gräber, (1990) Uni-site ATP synthesis in thylakoids. FEBS letters, 271(1): 116-118

DOI: 10.1016/0014-5793(90)80385-V.

Journal article.


1989

Fromme, P. and P. Gräber, (1989) Heterogeneity of ATP-hydrolyzing sites on reconstituted CF0F1. FEBS letters, 259(1): 33-36.

DOI: 10.1016/0014-5793(89)81487-5.

Journal article.


1988

Boekema, E.J., P. Fromme, and P. Gräber, (1988) On the Structure of the ATP‐Synthase from Chloroplasts. Berichte der Bunsengesellschaft für physikalische Chemie, 92(9): 1031-1036.

DOI: 10.1002/bbpc.198800257.

Journal article.


1987

Fromme, P. and P. Graber, (1987) The ATP-Synthetase from chloroplasts (CF0F1)-single site hydrolysis by the reconstituted enzyme and subunit composition of CF0. Biological Chemistry Hoppe-Seyler, 368(6): 553-556.

Journal article.

Fromme, P., E.J. Boekema, and P. Gräber, (1987) Isolation and characterization of a supramolecular complex of subunit III of the ATP-synthase from chloroplasts. Z. Naturforsch, 42c: 1239-1245.

Journal article.

Fromme, P., P. Gräber, and J. Salnikow, (1987) Isolation and identification of a fourth subunit in the membrane part of the chloroplast ATP-synthase. FEBS letters, 218(1): 27-30.

DOI: 10.1016/0014-5793(87)81011-6.

Journal article.


1986

Gräber, P., P. Fromme, U. Junesch, G. Schmidt, and G. Thulke, (1986) Kinetics of Proton-Transport-Coupled ATP Synthesis Catalyzed by the Chloroplast ATP Synthase. Berichte der Bunsengesellschaft für physikalische Chemie, 90(11): 1034-1040.

DOI: 10.1002/bbpc.19860901120.

Journal article.

Gräber, P., U. Junesch, G. Schmidt, and P. Fromme, (1986) Proton Transport-Coupled ATP Synthesis Catalyzed by the Chloroplast ATPase, in Ion Interactions in Energy Transfer Biomembranes, G.C. Papageorgiou, J. Barber, and S. Papa, Editors. Plenum Press: New York. p. 147-156.

DOI: 10.1007/978-1-4684-8410-6_15.

Book chapter.


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